DAPT is an inhibitor of the γ-secretase complex. Notch is a key target of γ-secretase, therefore DAPT indirectly inhibits the Notch pathway. Other targets of γ-secretase that would be influenced by DAPT include amyloid precursor protein, E-cadherin, and ErbB4. (Dovey et al.).
MAINTENANCE AND SELF-RENEWAL
· Reduces colony-forming efficiency of mouse neural stem cells (Androutsellis-Theotokis et al.).
· Enhances radiation-induced cell death of glioma stem cells (Wang et al.).
DIFFERENTIATION
· Promotes differentiation of nociceptors from human pluripotent stem cells, in combination with several other small molecules (Chambers et al.).
·

广州亿宁生物技术有限公司是一家专注细胞生物学试剂开发、销售、服务的高新技术企业。
1.进口胎牛血清：美国GIBCO、德国PAN-biotech、以色列BI、美国GEMINI、美国Hyclone等。
2.OriGen细胞冻存产品，TAKARA、Biolog微生物鉴定板、梅里埃试剂、Borer清洗液、台湾旭基产品。
3.Thermo、SIGMA、QIAGEN、MERCK、LEICA、Millipore、Whatman、MP Bio、日本同仁等。
好产品+好价格+好服务为经营理念，希望不断发展的广州亿宁成为您 的选择！

亿宁生物-陈月:
欢迎致电：19172390392  微信同号 二维码如下

·